Vitex agnus-castus L. د ا رسة الفعالية البايولوجية لبعض مستخلصات أو ا رق نبات كف مريم

Abstract

In this study, the antibacterial activity of some Leaves Extracts of (Vitex agnus-castus
L.)were determinated against two species of bacteria Escherichia coli and Staphylococcus
aurous, These extracts including hot ethanolic 70% extract , hot methanolic 70% extract
flavonoid extract , oil extract and essential oils extracts , and the anticancer activity of flavonoid
extract was evaluated against two cancer cell lines (HEP-2, AMN3 ).
The results showed that flavonoid extract exhibited best antibacterial activity followed by
hot ethanolic 70% extract and hot methanolic 70% extract , while oil extract and essential oils
extracts showed no antibacterial activity .
Anti cancer activity of flavonoid extract showed no anticancer activity against Hep-2and
AMN3 cell lines for three concentrations (3.125,6.25,12,5,25 mg/l) in comparison with negative
control. Moreover, a photochemical screening of the methanolic extract was revealed that
presence of flavonoids,tannins,saponins,phenols,and carbohydrates and absence of proteins and
alkaloids