Diagnostic Biomarkers Related to Cancer Detection and Treatment: A Review Article

Abstract

Cancer is a serious problem affecting the health of all human societies. Thus the challenge is how the diagnosis and then who find effective treatment. Proto-oncogenes under abnormal condition turn out to be oncogenes throughout genetic mutation, which is risky and preventing normal cell division and existing. Common mutations of p53 gene controlled on the disability of genes for replication. Advance and new molecular approaches that target the tumor cell or the tumor microenvironment was needed. Many molecular techniques like PCR, gene expressions, FISH & CISH,epigenetic signatures and  protein biomarker profiles, which in sequence allows to identifying the combination of biomarkers which may best recognize the presence or risk of cancer or check cancer therapies. Different techniques used to monitor the biomarker is essential to control the disease. Therefore, this study review aimed to clarification the most common methods used to diagnose the cancer related with some biomarkers.